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But seek medical care for a sudden "worst headache of your life," a headache with confusion, vision changes, chest pain, fainting, or a very fast/irregular heartbeat especially after heavy nicotine use

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Volkow and her colleagues reviewed the literature on pathophysiological processes that may hasten aging and are particularly relevant to smoking, second hand smoke, drug use, and addictions.6 They focused on oxidative stress and cellular aging, inflammation in periphery and brain, decline in brain volume and function, and early onset of cardiac, cerebrovascular, kidney, and liver disease

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